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purine nucleobases degradation I (anaerobic)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
hypoxanthine + acceptor + H2O <=> xanthine + reduced_acceptor 1.17.99.M4

formate + NAD+ <=> CO2 + NADH 1.17.1.10 formate dehydrogenase (NADP+)
1.17.1.9 formate dehydrogenase


4-aminoimidazole + H2O + H+ <=> NH3 + imidazolinone 3.5.4.8 aminoimidazolase

5-formimidoyltetrahydrofolate + glycine <=> Formiminoglycine + tetrahydrofolate 2.1.2.4 glycine formimidoyltransferase

5-formimidoyltetrahydrofolate + H+ <=> NH3 + 5,10-methenyltetrahydrofolate 4.3.1.4 formimidoyltetrahydrofolate cyclodeaminase

xanthine + H2O <=> H+ + 5-ureido-4-imidazole_carboxylate 3.5.2

5,10-methenyltetrahydrofolate + H2O <=> 10-formyltetrahydrofolate + H+ 3.5.4.9 methenyltetrahydrofolate cyclohydrolase

5-amino-4-imidazole_carboxylate <=> 4-aminoimidazole + CO2 4.1.1

ATP + acetate <=> ADP + acetyl_phosphate 2.1.2.2 phosphoribosylglycinamide formyltransferase
2.7.2.1 acetate kinase
2.7.2.15 propionate kinase
2.7.2.2 carbamate kinase




purine + H2O + acceptor <=> hypoxanthine + reduced_acceptor 1.17.99.M4

imidazolinone + H2O <=> Formiminoglycine 3.5.2

acetyl_phosphate + NH3 + thioredoxin_disulfide + H2O <=> glycine + phosphate + thioredoxin + H+ 1.21.4.2 glycine reductase

10-formyltetrahydrofolate + H2O <=> tetrahydrofolate + formate + H+ 3.5.1.10 formyltetrahydrofolate deformylase

5-ureido-4-imidazole_carboxylate + H2O + H+ <=> 5-amino-4-imidazole_carboxylate + CO2 + NH3 3.5.1
3.5.3


H+ + H2O + guanine <=> NH3 + xanthine 3.5.4.3 guanine deaminase

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